HCID 15675962, compound → HCID 15675987, compound

HRID 1533876Notes

Reaction equation

HRID 1533876 reaction equation
[F:1][C:2]1[C:3]([NH:12][CH2:13][C:14]2[CH2:23][CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=2)=[CH:4][C:5]2[O:9][C:8](=[O:10])[NH:7][C:6]=2[CH:11]=1>[C].[Pd]>[F:1][C:2]1[C:3]([NH:12][CH2:13][CH:14]2[CH2:23][CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15]2)=[CH:4][C:5]2[O:9][C:8](=[O:10])[NH:7][C:6]=2[CH:11]=1

Participants

3

Reactant 1

HCID 15675962HCID 15675962, compound

Product 1

HCID 15675987HCID 15675987, compound

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

In a manner similar to Example 3A starting with 5-fluoro-6-[(3,4-dihydro-2-naphthyl)methylamino]benzoxazolin-2-one but employing palladium carbon (5%) instead of platinum oxide, the title compound was prepared: m.p. 177°-178° C.

Sources & evidence

ORD record
ord-9c6319821c364ea68cf2931dd99bab08
Source dataset
uspto-grants-1992_02
Patent number
US05086062

Reaction notes

Loading…