Potassium Iodide → HCID 15030082, compound

HRID 1533919Notes

Reaction equation

HRID 1533919 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.Cl[CH2:15][CH2:16][CH:17]1[O:21][C:20](=[O:22])[N:19]([CH3:23])[CH2:18]1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([CH2:15][CH2:16][CH:17]2[O:21][C:20](=[O:22])[N:19]([CH3:23])[CH2:18]2)[CH2:10][CH2:9]1

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 705291-(2-Fluorophenyl)piperazineHCID 146987465-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one

Product 1

HCID 15030082HCID 15030082, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 3.6 g (0.02 mol) of 1-(2-fluorophenyl)piperazine (Emka-Chemie), 3.3 g (0.02 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 6.4 g (0.06 mol) of anhydrous sodium carbonate and 0.3 g of potassium iodide in 100 mL of 1-butanol gave 3.7 g (61%) of white solid, mp 80°-82° C.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-a85074ad11ed4b8daa3b0157bb849029
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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