1-(3-(Trifluoromethyl)phenyl)piperazine → HCID 15030102, compound

HRID 1533932Notes

Reaction equation

HRID 1533932 reaction equation
Cl[CH2:2][CH:3]1[O:7][C:6](=[O:8])[NH:5][CH2:4]1.[F:9][C:10]([F:24])([F:23])[C:11]1[CH:12]=[C:13]([N:17]2[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)[CH:14]=[CH:15][CH:16]=1>>[F:24][C:10]([F:9])([F:23])[C:11]1[CH:12]=[C:13]([N:17]2[CH2:22][CH2:21][N:20]([CH2:2][CH:3]3[O:7][C:6](=[O:8])[NH:5][CH2:4]3)[CH2:19][CH2:18]2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 42961-(3-(Trifluoromethyl)phenyl)piperazineHCID 908155-Chloromethyloxazolidin-2-one

Product 1

HCID 15030102HCID 15030102, compound

Procedure

Following the procedure of Example 35, the title compound was prepared from 5-chloromethyl-2-oxazolidinone and 1-(3-trifluoromethylphenyl)piperazine, mp 122°-124° C.

Sources & evidence

ORD record
ord-cc3bf9628ecd4c40aa88d7728b00fc17
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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