1-(2-Fluorophenyl)piperazine → 5-{2-[4-(2-Fluorophenyl)piperazin-1-yl]ethyl}-1,3-oxazolidin-2-one

HRID 1533933Notes

Reaction equation

HRID 1533933 reaction equation
Cl[CH2:2][CH2:3][CH:4]1[O:8][C:7](=[O:9])[NH:6][CH2:5]1.[F:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[N:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[F:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[N:17]1[CH2:22][CH2:21][N:20]([CH2:2][CH2:3][CH:4]2[O:8][C:7](=[O:9])[NH:6][CH2:5]2)[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 19911451HCID 19911451, compound

Product 1

HCID 150301035-{2-[4-(2-Fluorophenyl)piperazin-1-yl]ethyl}-1,3-oxazolidin-2-one

Procedure

Following the procedure of Example 35, the title compound was prepared from 5-(2-chloroethyl)-2-oxazolidinone and 1-(2-fluorophenyl)piperazine, mp 121°-124° C.

Sources & evidence

ORD record
ord-61afa4ebd61942d5b20ad03e3f1178c6
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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