HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → (2-hydroxyphenyl)-(1-methyl-1H-indol-4-yl) methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | (2-methoxyphenyl)-(1-methyl-1H-indol-4-yl) methanone | HCID 67854483 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (2-hydroxyphenyl)-(1-methyl-1H-indol-4-yl) methanone | HCID 67854425 | 60.7% |
Reaction Steps
Using the procedure of Step C of Example 3, 29.9 g of the product of Step C and 300 g of pyridine hydrochloride were reacted to obtain using methylene chloride as eluant for the chromatography 17.2 g of the expected product melting at 80° C. which was used as is for the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05086070 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-14a029a606614662ae77a4507290ca01 |
| Source note | uspto-grants-1992_02 |