5-(2-Benzyloxy-6-fluoro-4-iodophenyl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-one → {2-[3-Benzyloxy-4-(5-benzyloxymethyl-1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-5-fluorobenzyl]-5-methylphenyl}-carbamic acid tert-butyl ester

HRID 153408Notes

Reaction equation

HRID 153408 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([CH2:15][I:16])[cH:10][cH:11][c:12]([CH3:14])[cH:13]1)=[O:17].[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[O:25][c:26]1[c:27]([N:34]2[CH2:35][C:36](=[O:50])[N:37]([CH2:41][O:42][CH2:43][c:44]3[cH:45][cH:46][cH:47][cH:48][cH:49]3)[S:38]2(=[O:39])=[O:40])[c:28]([F:33])[cH:29][c:30]([I:32])[cH:31]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([CH2:15][c:30]2[cH:29][c:28]([F:33])[c:27]([N:34]3[CH2:35][C:36](=[O:50])[N:37]([CH2:41][O:42][CH2:43][c:44]4[cH:45][cH:46][cH:47][cH:48][cH:49]4)[S:38]3(=[O:39])=[O:40])[c:26]([O:25][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:31]2)[cH:10][cH:11][c:12]([CH3:14])[cH:13]1)=[O:17]

Participants

3

Reactant 2

HCID 684293105-(2-Benzyloxy-6-fluoro-4-iodophenyl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-oneHCID 68429608(2-Iodomethyl-5-methylphenyl)-carbamic acid tert-butyl ester

Product 1

HCID 68429549{2-[3-Benzyloxy-4-(5-benzyloxymethyl-1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-5-fluorobenzyl]-5-methylphenyl}-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-57b01524f7d543c18fc7dba028e96c92
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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