Ethanol → HCID 15008971, compound

Participants

Reaction Steps

2-(3,4-Dimethoxyphenyl)ethylamine (80.0g), 2-bromoethanol (182 g) and potassium carbonate (201 g) were added to ethanol (1 () and the mixture was refluxed for 16 hours. After cooling, the mixture was filtered and the filtrate was concentrated in vacuo. The oily residue was dissolved in chloroform. The solution was washed with saturated sodium chloride solution, dried over anhydrous magnesium sulfate and concentrated in vacuo to give 104.5 g(88% ) of N,N-bis(2-hydroxyethyl)-2-(3,4-dimethoxyphenyl)ethylamine in oily form.

Provenance & Evidence