Diethylamine → 3-Hydroxy-2-cyclobuten-1-one-diethylammonium salt

HRID 1534179노트

반응식

HRID 1534179 반응식
[C:1]1(=[O:6])[CH2:4][C:3](=[O:5])[CH2:2]1.[CH2:7]([NH:9][CH2:10][CH3:11])[CH3:8]>C(OCC)(=O)C>[CH2:7]([NH2+:9][CH2:10][CH3:11])[CH3:8].[OH:6][C:1]1[CH2:4][C:3](=[O:5])[CH:2]=1

참가 물질

4

반응물 2

HCID 8021DiethylamineHCID 27357Cyclobutane-1,3-dione

생성물 1

HCID 198960273-Hydroxy-2-cyclobuten-1-one-diethylammonium salt수율 83.8%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매2회

실험 절차

2.1 g of 1,3-cyclobutanedione (23.0 mmol) was suspended in 40 g of ethyl acetate. A solution of 1.84 g of diethylamine (25.0 mmol) in 10 g of ethyl acetate was instilled in this suspension at 20° C. within 15 minutes. After 1 hour of stirring at room temperature, the suspension was filtered and then dried. 3.05 g of the title product with a purity (according to HPLC) of 93.7 percent, corresponding to a yield of 79.2 percent, relative to the cyclobutanedione, was obtained. Data for the title compound was:

후처리

  1. filtrationthe suspension was filtered
  2. customdried

출처 및 근거

ORD 기록
ord-991935a52a47499ba791437cd5074fb3
출처 데이터셋
uspto-grants-1992_02
특허 번호
US05087756

반응 노트

불러오는 중…