HCID 15029666, compound → HCID 15029667, compound

HRID 1534235Notes

Reaction equation

HRID 1534235 reaction equation
[CH3:1][O:2][C:3]1[CH:31]=[CH:30][C:6]([C:7]([C:9]2[O:10][C:11]3[C:18]([CH2:19][CH2:20][CH3:21])=[CH:17][CH:16]=[C:15]([O:22]CC4C=CC=CC=4)[C:12]=3[C:13]=2[CH3:14])=O)=[CH:5][CH:4]=1>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][C:9]2[O:10][C:11]3[C:18]([CH2:19][CH2:20][CH3:21])=[CH:17][CH:16]=[C:15]([OH:22])[C:12]=3[C:13]=2[CH3:14])=[CH:30][CH:31]=1

Participants

4

Reactant 1

HCID 15029666HCID 15029666, compound

Product 1

HCID 15029667HCID 15029667, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 2-(p-methoxybenzoyl)-3-methyl-4-benzyloxy-7-propylbenzofuran (0.10 gm, 0.24 mmole) in ethanol was hydrogenated in a Parr hydrogenator in the presence of 10% palladium on charcoal at 40 psi for a period of 7 hours. The catalyst was filtered off, washed with some ethanol, and the filtrate was concentrated in vacuo to yield 2-(p-methoxybenzyl)-3-methyl-4-hydroxy-7-propylbenzofuran.

Workup

  1. filtrationThe catalyst was filtered off
  2. washwashed with some ethanol
  3. concentrationthe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-0dc62a990d9a437cb4af1e7e27b0db22
Source dataset
uspto-grants-1992_02
Patent number
US05087638

Reaction notes

Loading…