HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 14570908, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | HCID 14570907 | HCID 14570907 | — |
| Reactant | Jones' reagent | HCID 131709961 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 14570908 | HCID 14570908 | — |
Reaction Steps
To a solution of the silyated phenol derivative of (180) (Example 49) (400 mg, 0.84 mmol) in 10 mL acetone was added dropwise at 0° C. the Jones reagent. The reaction was monitored by tlc. The crude silylated acid after workup was treated with tetra-n-butyl ammonium fluoride as described before. The title compound was isolated by preparative tlc, mp 149°-151° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05087638 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-b8a1fed0757a4e6c91943e651fbceffd |
| Source note | uspto-grants-1992_02 |