HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → Methyl 2-(methoxymethylidene)-3-oxopentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Trimethyl orthoformate | HCID 9005 | — |
| Reactant | Methyl 3-oxovalerate | HCID 121699 | — |
| Product | Methyl 2-(methoxymethylidene)-3-oxopentanoate | HCID 53662896 | — |
Reaction Steps
A mixture of methyl propionylacetate (112.2 g, 0.86 mol), trimethyl orthoformate (188 ml, 1.72 mol) and acetic anhydride (81 ml, 0.86 mol) was heated at reflux for 17 hours, then the volatile material removed in vacuo, finally at 70°/0.3mm. The residue was predominantly methyl 2-propanoyl-3-methoxyacrylate, and was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05089504 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-12c713b72b264238b420b4c679e343a6 |
| Source note | uspto-grants-1992_02 |