HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178459173, compound → HCID 10036866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178459173 | HCID 178459173 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 10036866 | HCID 10036866 | 53.1% |
Reaction Steps
Methyl 2-propanoyl-3-(2-methoxyphenylamino)acrylate (77.7 g, 0.29 mol) was added to boiling diphenyl ether (500 ml) then heated at reflux for 1 hour. The solution was partially cooled and poured into high-boiling petroleum ether, then the solid filtered off and washed with 40-60 petroleum ether to give 3-propanoyl-8-methoxy-4(1H)-quinolone (35.6 g, 52%), m.p. 260°-263°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05089504 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-e65e68c368dd4b7484f927f095be983b |
| Source note | uspto-grants-1992_02 |