7-Methoxy-4-cyano chrom-3-ene → HCID 15023228, compound

HRID 1534529Notes

Reaction equation

HRID 1534529 reaction equation

[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([C:7]([C:13]#[N:14])=[CH:8][CH2:9][O:10]2)=[CH:5][CH:4]=1>CO.N.[Ni]>[NH2:14][CH2:13][CH:7]1[C:6]2[C:11](=[CH:12][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[O:10][CH2:9][CH2:8]1

Participants

5

Reactant 1

HCID 150232277-Methoxy-4-cyano chrom-3-ene

Product 1

HCID 15023228HCID 15023228, compound

Reagents, catalysts & solvents 3

HCID 935NickelCatalyst

HCID 222AmmoniaSolvent

HCID 887MethanolSolvent

Procedure

The product from Example 1 was hydrogenated with RaNi in MeOH and NH3 at 4 atm. pressure and gave the desired product, (M+H)+ 194.

Sources & evidence

ORD record: ord-7c76b4cb7be64bee8b97ed1d234aca83
Source dataset: uspto-grants-1992_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05089519

Reaction notes

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