Chlorosulfonic acid → HCID 19910021, compound

HRID 1534631Notes

Reaction equation

HRID 1534631 reaction equation
Cl[S:2]([OH:5])(=[O:4])=[O:3].[CH:6]([N:8]1[C:21]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[S:15][C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2)=[O:7]>>[CH:6]([N:8]1[C:9]2[CH:10]=[C:11]([S:2]([OH:5])(=[O:4])=[O:3])[CH:12]=[CH:13][C:14]=2[S:15][C:16]2[C:21]1=[CH:20][CH:19]=[CH:18][CH:17]=2)=[O:7]

Participants

3

Reactant 2

HCID 24638Chlorosulfonic acidHCID 11138870Phenothiazine-10-carboxadehyde

Product 1

HCID 19910021HCID 19910021, compoundYield 75%

Conditions

Temperature
20 °C

Procedure

Into a reactor, equipped with mechanical stirrer and thermometer, chlorosulfonic acid (17.49 g) and, slowly under stirring, N-formyl-phenothiazine (7.5 g) were charged, under nitrogen at 20° C. The reaction mixture was left under stirring at 20° C. for 3 hours. The HPLC analysis showed the formation of N-formyl-phenothiazine-2-sulfonic acid (75% yield).

Workup

  1. customInto a reactor, equipped with mechanical stirrer
  2. waitThe reaction mixture was left

Sources & evidence

ORD record
ord-17b7222032a74ebfb144cbe5dd846b54
Source dataset
uspto-grants-1992_02
Patent number
US05089613

Reaction notes

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