3-Ethyl-3,5,5-trimethylmorpholin-2-one → 2-[(1-Hydroxy-2-methylpropan-2-yl)amino]-2-methylbutan-1-ol

Participants

Reaction Steps

In a manner analogous to that described in example 3A hereinabove, 3-methyl,3-ethyl-5,5-dimethyl-2-morpholone is reduced with LiAlH4 to provide a better than 80% yield of (1-hydroxy-2-methyl-2-propyl)(1-hydroxy-2-methyl-2-butyl)amine which has a bp of 136°-7° C./4 mm Hg.

Provenance & Evidence