(5-Chloro-2-oxo-2,3-dihydrobenzimidazol-1-yl)phenyl-acetic acid → 6-chloro-3-[2-oxo-1-phenyl-2-(4-pyridin-4-ylpiperazin-1-yl)ethyl]-1H-benzimidazol-2-one
Reaction equation
[Cl:32][c:33]1[cH:34][cH:35][c:36]2[n:37]([CH:38]([c:39]3[cH:40][cH:41][cH:42][cH:43][cH:44]3)[C:45]([OH:46])=[O:47])[c:48](=[O:49])[nH:50][c:51]2[cH:52]1.[O:1]=[C:2]([CH:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[n:10]1[c:11](=[O:19])[nH:12][c:13]2[c:14]1[cH:15][cH:16][cH:17][cH:18]2)[N:20]1[CH2:21][CH2:22][N:23]([c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[CH2:24][CH2:25]1>>[O:1]=[C:2]([CH:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[n:10]1[c:11](=[O:19])[nH:12][c:13]2[c:14]1[cH:15][cH:16][c:17]([Cl:32])[cH:18]2)[N:20]1[CH2:21][CH2:22][N:23]([c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[CH2:24][CH2:25]1Participants
3
Sources & evidence
- ORD record
- ord-91b1e00270774f53bebdad80593c330d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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