反应详情

温度

83 °C

In a 100 ml-three-necked flask, 1.30 g (5.90 mM) of 4-hexylbenzohydrazide was placed and a solution of the above-prepared 6-acetoxy-2-naphthoyl chloride in 45 ml of dioxane was added thereto, followed by heating to about 83° C. To the mixture, 2.20 ml of pyridine was added under stirring, followed by stirring for 25 minutes at 83°-83.5° C. After the reaction, the reaction mixture was cooled on an iced water bath and poured into 300 ml of iced water to precipitate a crystal. The crystal was recovered by filtration, followed by washing with water and further washing with methanol to obtain 2.22 g of N-4-hexylbenzoyl-N'-(6-acetoxy-2-naphthoyl)hydrazine (Yield: 87.0%). ##STR33##

1. stirringby stirring for 25 minutes at 83°-83.5° C
2. customAfter the reaction
3. temperaturethe reaction mixture was cooled on an iced water bath
4. customto precipitate a crystal
5. filtrationThe crystal was recovered by filtration
6. washby washing with water
7. washfurther washing with methanol