HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → HCID 136142366, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Ethyl 3-(6-oxo-3,6-dihydro-9H-purin-9-yl)propanoate | HCID 135794781 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 136142366 | HCID 136142366 | 92% |
Reaction Steps
1.500 g (25.0 mmol) of ethylenediamine was stirred at room temperature with 250 mg (1.06 mmol) of 3-(1,6-dihydro-6-oxo-9H-purin-9-yl)propionic acid, ethyl ester (AIT-0027) for one hour. The solution was treated with 4 ml acetonitrile and 20 ml of ether with stirring. Upon filtration and washing with ether, this yielded 245 mg of 3-(1,6-dihydro-6-oxo-9H-purin-9-yl)-N-(2-aminoethyl)propanamide (AIT-0058) as a slightly yellow solid. Yield: 92%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05091432 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-6040615d4ac6418db32c57129af9ecd8 |
| Source note | uspto-grants-1992_02 |