Dimethyl Sulfoxide → N-methyl-4-(2-(4-(4-phenylphthalazin-1-yloxy)phenoxy)pyridin-3-yl)pyrimidin-2-amine

HRID 1535133Notes

Reaction equation

HRID 1535133 reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[CH3:18][NH:19][c:20]1[n:21][cH:22][cH:23][c:24](-[c:26]2[c:27]([O:32][c:33]3[cH:34][cH:35][c:36]([OH:39])[cH:37][cH:38]3)[n:28][cH:29][cH:30][cH:31]2)[n:25]1.[CH3:46][S:47]([CH3:48])=[O:49].[CH3:50][OH:51].[Cl:1][c:2]1[n:3][n:4][c:5](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[K+:44].[K+:45]>>[c:2]1([O:39][c:36]2[cH:35][cH:34][c:33]([O:32][c:27]3[c:26](-[c:24]4[cH:23][cH:22][n:21][c:20]([NH:19][CH3:18])[n:25]4)[cH:31][cH:30][cH:29][n:28]3)[cH:38][cH:37]2)[n:3][n:4][c:5](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 887MethanolHCID 19660Carbonate IonHCID 2721091-Chloro-4-phenylphthalazineHCID 66732110HCID 66732110, compound

Product 1

HCID 57756246N-methyl-4-(2-(4-(4-phenylphthalazin-1-yloxy)phenoxy)pyridin-3-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-7c4937d8dd39499bb24ea620386bd062
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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