5-amino-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one → N2-(2-Oxo-2,3-dihydro-1H-indol-4-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)glycinamide

HRID 1535271Notes

Reaction equation

HRID 1535271 reaction equation
[NH2:16][c:17]1[cH:18][c:19]2[c:23]([cH:24][cH:25]1)[CH2:22][C:21]1([CH2:20]2)[C:26](=[O:34])[NH:27][c:28]2[n:29][cH:30][cH:31][cH:32][c:33]21.[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][cH:7][c:8]([NH:11][CH2:12][C:13](=[O:14])[OH:15])[c:9]2[CH2:10]1>>[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][cH:7][c:8]([NH:11][CH2:12][C:13](=[O:15])[NH:16][c:17]3[cH:18][c:19]4[c:23]([cH:24][cH:25]3)[CH2:22][C:21]3([CH2:20]4)[C:26](=[O:34])[NH:27][c:28]4[n:29][cH:30][cH:31][cH:32][c:33]43)[c:9]2[CH2:10]1

Participants

3

Reactant 2

HCID 591667225-amino-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-oneHCID 59322832N-(2-Oxo-2,3-dihydro-1H-indol-4-yl)glycine

Product 1

HCID 59648420N2-(2-Oxo-2,3-dihydro-1H-indol-4-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)glycinamide

Sources & evidence

ORD record
ord-9aa39bc405104c0986a87e0828243665
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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