1-Benzyl-4-piperidylamine → [2-Amino-6-(1-benzyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-phenyl)-methanone
Reaction equation
[NH2:1][c:2]1[n:3][c:4]([Cl:19])[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1.[NH2:20][CH:21]1[CH2:22][CH2:23][N:24]([CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:25][CH2:26]1>>[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][N:24]([CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:25][CH2:26]2)[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1Participants
3
Sources & evidence
- ORD record
- ord-907254b7e2034a58a1009ded731a5005
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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