Methanol → 2,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid

HRID 1535641Notes

Reaction equation

HRID 1535641 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([c:10]1[c:11]([F:24])[c:12]([NH:17][S:18](=[O:19])(=[O:20])[CH2:21][CH2:22][CH3:23])[cH:13][cH:14][c:15]1[F:16])=[O:25].[CH3:26][OH:27].[OH-:28].[OH-:30].[Pd+2:29]>>[O:8]=[C:9]([c:10]1[c:11]([F:24])[c:12]([NH:17][S:18](=[O:19])(=[O:20])[CH2:21][CH2:22][CH3:23])[cH:13][cH:14][c:15]1[F:16])[OH:25]

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 53396460Benzyl 2,6-difluoro-3-(propane-1-sulfonamido)benzoate

Product 1

HCID 461929232,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid

Sources & evidence

ORD record
ord-13b1a49044c543b9a63c865c5ca82550
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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