N-BOC-ethylenediamine → tert-butyl 2-[(2-amino-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-4-yl)amino]ethylcarbamate

HRID 1535802Notes

Reaction equation

HRID 1535802 reaction equation
[Cl:12][c:13]1[c:14]2[c:15]([n:16][c:17]([NH2:19])[n:18]1)-[c:20]1[c:21]([cH:25][cH:26][cH:27][cH:28]1)[CH2:22][CH2:23][CH2:24]2.[NH2:1][CH2:2][CH2:3][NH:4][C:5]([O:6][C:7]([CH3:8])([CH3:9])[CH3:10])=[O:11]>>[NH:1]([CH2:2][CH2:3][NH:4][C:5]([O:6][C:7]([CH3:8])([CH3:9])[CH3:10])=[O:11])[c:13]1[c:14]2[c:15]([n:16][c:17]([NH2:19])[n:18]1)-[c:20]1[c:21]([cH:25][cH:26][cH:27][cH:28]1)[CH2:22][CH2:23][CH2:24]2

Participants

3

Reactant 2

HCID 187201N-BOC-ethylenediamineHCID 866218984-chloro-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine

Product 1

HCID 68604420tert-butyl 2-[(2-amino-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-4-yl)amino]ethylcarbamate

Sources & evidence

ORD record
ord-b599affde9f7438faedeed4b2e40004a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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