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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1535831Generated: November 4, 2026

Chloride → 8-(2-Methyl-propane-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/1535831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantHeptaneHCID 8900—
Reactant4-(Trifluoromethoxy)anilineHCID 600848—
ReactantDimethylalumanyliumHCID 16685399—
Reactant4-(2-Methoxy-ethyl)-1-(2-methyl-propane-1-sulfonyl)-piperidine-4-carboxylic acid ethyl esterHCID 66787088—
Product8-(2-Methyl-propane-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 49802245—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-530d3762648a42e0bab9f76dcb0fb7e7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)