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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1535833Generated: November 3, 2026

5-chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiophene-2-sulfonamide → 5-[7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

https://huagongshe.com/reaction/1535833

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiophene-2-sulfonamideHCID 22500823—
Reactant3-Ethynyl-7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidineHCID 86608034—
Product5-[7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amideHCID 67000732—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-79459384e1284cda9ea8d49733c744b5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)