Methanol → Tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

HRID 1535920Notes

Reaction equation

[BH4-:15].[C:1]([CH3:2])(=[O:3])[CH:4]1[CH2:5][N:6]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:7]1.[CH3:17][OH:18].[Na+:16]>>[CH:1]([CH3:2])([OH:3])[CH:4]1[CH2:5][N:6]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:7]1

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium ion

HCID 28123Borohydride

HCID 59841137tert-Butyl 3-acetylazetidine-1-carboxylate

Product 1

HCID 58348207Tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

Sources & evidence

ORD record: ord-839e7b4cddf84fa88fc2adf61a7ea668
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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