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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1536Generated: October 26, 2026

(2S)-2-{[4-(benzyloxy)phenoxy]methyl}oxirane → (S)-4-{2-[2-hydroxy-3-(4-benzyloxyphenoxy)propylamino]ethyl}phenoxymethylcyclohexylphosphinic acid, n-butyl ester

https://huagongshe.com/reaction/1536

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-{[4-(benzyloxy)phenoxy]methyl}oxiraneHCID 11817709—
Reactant4-(2-Aminoethyl)phenoxy methylcyclohexylphosphinic acid, n-butyl esterHCID 86752198—
Product(S)-4-{2-[2-hydroxy-3-(4-benzyloxyphenoxy)propylamino]ethyl}phenoxymethylcyclohexylphosphinic acid, n-butyl esterHCID 86752197—

Reaction Steps

The title compound was prepared from 4-(2-aminoethyl)phenoxy methylcyclohexylphosphinic acid, n-butyl ester and (S)-2-(4-benzyloxyphenoxymethyl)oxirane according to the method described in Procedure 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05726165
Source datasetuspto-grants-1998_03
ORD IDord-d63aff1397e8480b8c2a33699be1bede
Source noteuspto-grants-1998_03