N-[6-(3,3-dimethylbutylamino)-3-hydroxy-5-methyl-6-oxo-1-phenylhexan-2-yl]-3-methylsulfonylbenzamide → N-[6-(2-bicyclo[2.2.1]heptanylamino)-3-hydroxy-5-methyl-6-oxo-1-phenylhexan-2-yl]-3-methylsulfonyl-5-(2-oxopyrrolidin-1-yl)benzamide
Reaction equation
[CH2:1]([CH:2]([NH:3][C:4](=[O:5])[c:6]1[cH:7][cH:8][cH:9][c:10]([S:11]([CH3:12])(=[O:13])=[O:14])[cH:15]1)[CH:16]([OH:17])[CH2:18][CH:19]([C:20](=[O:21])[NH:22][CH2:23][CH2:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH3:29])[c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[CH3:36][S:37](=[O:38])(=[O:39])[c:40]1[cH:41][c:42]([C:43](=[O:44])[OH:45])[cH:46][c:47]([N:49]2[C:50](=[O:54])[CH2:51][CH2:52][CH2:53]2)[cH:48]1.[CH:55]12[CH:56]([NH:62][C:63]([CH:64]([CH2:65][CH:66]([CH:67]([CH2:68][c:69]3[cH:70][cH:71][cH:72][cH:73][cH:74]3)[NH2:75])[OH:76])[CH3:77])=[O:78])[CH2:57][CH:58]([CH2:59][CH2:60]1)[CH2:61]2>>[CH3:36][S:37](=[O:38])(=[O:39])[c:40]1[cH:41][c:42]([C:43](=[O:45])[NH:75][CH:67]([CH:66]([CH2:65][CH:64]([C:63]([NH:62][CH:56]2[CH:55]3[CH2:60][CH2:59][CH:58]([CH2:57]2)[CH2:61]3)=[O:78])[CH3:77])[OH:76])[CH2:68][c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[cH:46][c:47]([N:49]2[C:50](=[O:54])[CH2:51][CH2:52][CH2:53]2)[cH:48]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-99d615f7216841ae8410d8af364ce4a5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…