7-(Trifluoromethyl)-1,2,3,4-tetrahydroquinoline → 4-Methyl-2-[4'-trifluoromethyl-5-(7-trifluoromethyl-3,4-dihydro-2H-quinolin-1-yl)-biphenyl-3-yl]-pentanoic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]([CH3:7])[CH3:8])[c:9]1[cH:10][c:11](-[c:23]2[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]2)[cH:12][c:13]([O:15][S:16]([C:17]([F:18])([F:19])[F:20])(=[O:21])=[O:22])[cH:14]1)=[O:33].[F:34][C:35]([c:36]1[cH:37][cH:38][c:39]2[c:44]([cH:45]1)[NH:43][CH2:42][CH2:41][CH2:40]2)([F:46])[F:47]>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]([CH3:7])[CH3:8])[c:9]1[cH:10][c:11](-[c:23]2[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]2)[cH:12][c:13]([N:43]2[CH2:42][CH2:41][CH2:40][c:39]3[cH:38][cH:37][c:36]([C:35]([F:34])([F:46])[F:47])[cH:45][c:44]32)[cH:14]1)=[O:33]Participants
3
Sources & evidence
- ORD record
- ord-07427447bc00453eb4889b6cea85832b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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