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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1536422Generated: October 31, 2026

Tetrahydrofuran → 5-Bromo-1-{(3SR,4RS)-3-(3,4-dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidin-1-yl}-pentan-1-one

https://huagongshe.com/reaction/1536422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant5-Bromovaleryl chlorideHCID 521173—
Reactant[(3RS,4SR)-4-(3,4-Dichloro-phenyl)-pyrrolidin-3-yl]-(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amineHCID 75231672—
Product5-Bromo-1-{(3SR,4RS)-3-(3,4-dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidin-1-yl}-pentan-1-oneHCID 72253475—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-6afc408c11f94efd9a465836c4eef0bb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)