N-[4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]-2-pyrrolidin-1-yl-isonicotinamide → N-[2',6-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-yl]-2-(1-pyrrolidinyl)-4-pyridinecarboxamide

HRID 1536484Notes

Reaction equation

HRID 1536484 reaction equation
[Br:1][c:2]1[c:3]([CH3:14])[cH:4][c:5](-[c:8]2[o:9][c:10]([CH3:13])[n:11][n:12]2)[cH:6][cH:7]1.[CH3:15][c:16]1[c:17]([B:36]2[O:37][C:38]([CH3:39])([CH3:40])[C:41]([CH3:42])([CH3:43])[O:44]2)[cH:18][c:19]([NH:22][C:23](=[O:24])[c:25]2[cH:26][c:27]([N:31]3[CH2:32][CH2:33][CH2:34][CH2:35]3)[n:28][cH:29][cH:30]2)[cH:20][cH:21]1>>[c:2]1(-[c:17]2[c:16]([CH3:15])[cH:21][cH:20][c:19]([NH:22][C:23](=[O:24])[c:25]3[cH:26][c:27]([N:31]4[CH2:32][CH2:33][CH2:34][CH2:35]4)[n:28][cH:29][cH:30]3)[cH:18]2)[c:3]([CH3:14])[cH:4][c:5](-[c:8]2[o:9][c:10]([CH3:13])[n:11][n:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 11258289N-[4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]-2-pyrrolidin-1-yl-isonicotinamideHCID 114366932-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole

Product 1

HCID 10479082N-[2',6-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-yl]-2-(1-pyrrolidinyl)-4-pyridinecarboxamide

Sources & evidence

ORD record
ord-fa0aca72d164423eaa4a8145f872b413
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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