1-Amino-2-cyclopropylpropan-2-ol → N-(2-cyclopropyl-2-hydroxypropyl)-6-(cyclopropylmethoxy)-5-(4-fluorophenyl)pyridine-3-carboxamide
Reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([O:17][CH2:18][CH:19]3[CH2:20][CH2:21]3)[n:10][cH:11][c:12]([C:13](=[O:14])[OH:15])[cH:16]2)[cH:6][cH:7]1.[NH2:22][CH2:23][C:24]([OH:25])([CH:26]1[CH2:27][CH2:28]1)[CH3:29]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([O:17][CH2:18][CH:19]3[CH2:20][CH2:21]3)[n:10][cH:11][c:12]([C:13](=[O:15])[NH:22][CH2:23][C:24]([OH:25])([CH:26]3[CH2:27][CH2:28]3)[CH3:29])[cH:16]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-d4d4532316814996991ce8497a74638e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…