Acetic Acid → 5-(3-Bromo-5-morpholinomethyl-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]-oxadiazole

HRID 1537326Notes

Reaction equation

HRID 1537326 reaction equation
[Br:1][c:2]1[c:3](-[c:9]2[n:10][c:11](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[n:12][o:13]2)[o:4][c:5]([CH:7]=[O:8])[cH:6]1.[C:21]([BH3-:22])#[N:23].[CH2:29]1[CH2:30][O:31][CH2:32][CH2:33][NH:34]1.[CH3:25][C:26](=[O:27])[OH:28].[CH3:35][OH:36].[Na+:24]>>[Br:1][c:2]1[c:3](-[c:9]2[n:10][c:11](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[n:12][o:13]2)[o:4][c:5]([CH2:7][N:34]2[CH2:29][CH2:30][O:31][CH2:32][CH2:33]2)[cH:6]1

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 887MethanolHCID 923Sodium ionHCID 8083MorpholineHCID 498716Cyano-borohydrideHCID 221478875-(3-Bromo-5-formyl-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]-oxadiazole

Product 1

HCID 221478365-(3-Bromo-5-morpholinomethyl-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]-oxadiazole

Sources & evidence

ORD record
ord-6443940a11614148b62e245d0f54b1bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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