Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1537349Generated: November 4, 2026

Sodium ion → Tert-butyl 3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-(4-fluorophenyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1537349

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
Reactant3,5-Bis(trifluoromethyl)benzyl bromideHCID 122573—
ReactantHydrideHCID 166653—
ReactantTert-butyl 4-(4-fluorophenyl)-3-(hydroxymethyl)piperidine-1-carboxylateHCID 22643987—
ProductTert-butyl 3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-(4-fluorophenyl)piperidine-1-carboxylateHCID 87709211—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-9a23d028437d430eb76ad00bbe751e44
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)