4-(4-(Trifluoromethyl)phenoxy)piperidine → 1-{[5-(4-Methylphenyl)isoxazol-4-yl]carbonyl}-4-[4-(trifluoromethyl)phenoxy]piperidine
Reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:13](=[O:14])[OH:15])[cH:10][n:11][o:12]2)[cH:6][cH:7]1.[F:16][C:17]([c:18]1[cH:19][cH:20][c:21]([O:22][CH:23]2[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]2)[cH:29][cH:30]1)([F:31])[F:32]>>[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:13](=[O:15])[N:26]3[CH2:25][CH2:24][CH:23]([O:22][c:21]4[cH:20][cH:19][c:18]([C:17]([F:16])([F:31])[F:32])[cH:30][cH:29]4)[CH2:28][CH2:27]3)[cH:10][n:11][o:12]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-c774e076e2fa4427bce5a9f38e622007
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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