1-(Bromomethyl)-4-(trifluoromethyl)benzene → Ethyl 4-methyl-2-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiazole-5-carboxylate
Reaction equation
[Br:1][CH2:2][CH:3]1[CH2:4][C:5]1([F:6])[F:7].[CH3:20][c:21]1[n:22][c:23]([N:31]2[C:32](=[O:36])[NH:33][CH2:34][CH2:35]2)[s:24][c:25]1[C:26](=[O:27])[O:28][CH2:29][CH3:30].[F:8][C:9]([c:10]1[cH:11][cH:12][c:13]([CH2:14][Br:15])[cH:16][cH:17]1)([F:18])[F:19]>>[F:8][C:9]([c:10]1[cH:11][cH:12][c:13]([CH2:14][N:33]2[C:32](=[O:36])[N:31]([c:23]3[n:22][c:21]([CH3:20])[c:25]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[s:24]3)[CH2:35][CH2:34]2)[cH:16][cH:17]1)([F:18])[F:19]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a5a30548f11649d99638f6b0ada47db9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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