Dimethyl Sulfoxide → 8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxyquinolin-2(1H)-one
Reaction equation
[CH3:38][S:39]([CH3:40])=[O:41].[Cl:23][c:24]1[cH:25][n:26][cH:27][c:28]([Cl:31])[c:29]1[Cl:30].[H-:21].[K+:37].[NH2:1][c:2]1[cH:3][c:4](=[O:20])[nH:5][c:6]2[c:7]([O:14][CH:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[c:8]([O:12][CH3:13])[cH:9][cH:10][c:11]12.[Na+:22].[P:32]([O-:33])([OH:34])([OH:35])=[O:36]>>[NH:1]([c:2]1[cH:3][c:4](=[O:20])[nH:5][c:6]2[c:7]([O:14][CH:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[c:8]([O:12][CH3:13])[cH:9][cH:10][c:11]12)[c:29]1[c:24]([Cl:23])[cH:25][n:26][cH:27][c:28]1[Cl:31]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b0efe8e11fba434d90270f3d8f3913ee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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