Pyridine → 2-[(4-tert-butylbenzyl)amino]-1-(5-isoquinolinyl)-2-oxoethyl Methanesulfonate

HRID 1537888Notes

Reaction equation

HRID 1537888 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][NH:10][C:11]([CH:12]([c:13]2[c:14]3[cH:15][cH:16][n:17][cH:18][c:19]3[cH:20][cH:21][cH:22]2)[OH:23])=[O:24])[cH:25][cH:26]1.[CH3:27][S:28]([Cl:29])(=[O:30])=[O:31].[cH:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][NH:10][C:11]([CH:12]([c:13]2[c:14]3[cH:15][cH:16][n:17][cH:18][c:19]3[cH:20][cH:21][cH:22]2)[O:23][S:28]([CH3:27])(=[O:30])=[O:31])=[O:24])[cH:25][cH:26]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 31297Methanesulfonyl chlorideHCID 11291000N-(4-tert-butylbenzyl)-2-hydroxy-2-(5-isoquinolinyl)acetamide

Product 1

HCID 574338452-[(4-tert-butylbenzyl)amino]-1-(5-isoquinolinyl)-2-oxoethyl Methanesulfonate

Sources & evidence

ORD record
ord-fcca1fb256b04682aa63ae2b427bd0b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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