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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1538305Generated: October 26, 2026

Dimethylformamide → 5-(1-carbamoyl-5-chloro-2-oxo-3H-indole-3-carbonyl)thiophene-2-carboxylic acid

https://huagongshe.com/reaction/1538305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant2,5-Thiophenedicarboxylic acidHCID 20273—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant5-Chloro-2-oxo-2,3-dihydro-1H-indole-1-carboxamideHCID 9859159—
Product5-(1-carbamoyl-5-chloro-2-oxo-3H-indole-3-carbonyl)thiophene-2-carboxylic acidHCID 70221222—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-b28a5ab0768847bda54d849096d1cd63
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)