Sodium ion → N-t-BOC-trans-4-Fluoro-L-Prolinonitrile

HRID 1538386Notes

Reaction equation

HRID 1538386 reaction equation
[C:1](#[N:2])[CH:3]1[N:4]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:5][CH:6]([OH:8])[CH2:7]1.[CH2:16]([N:17]([S:18]([F:19])([F:20])[F:22])[CH2:21][CH3:23])[CH3:24].[Cl:32][CH2:33][Cl:34].[Na+:25].[Na+:26].[O-:27][C:28](=[O:29])[O-:30].[OH2:31]>>[C:1](#[N:2])[CH:3]1[N:4]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:5][CH:6]([F:22])[CH2:7]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 123472(Diethylamino)sulfur trifluorideHCID 68626765Tert-butyl 2-cyano-4-hydroxy-pyrrolidine-1-carboxylate

Product 1

HCID 17856495N-t-BOC-trans-4-Fluoro-L-Prolinonitrile

Sources & evidence

ORD record
ord-904b2be6aec84f5aa9202803c6c33681
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…