Acetate → N-(5-(2-Amino-3-(3-fluorophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-chloropyridin-3-yl)methanesulfonamide

HRID 1538502Notes

Reaction equation

HRID 1538502 reaction equation
[CH3:36][C:37](=[O:38])[O-:39].[CH3:40][OH:41].[Cl:1][c:2]1[c:3]([NH:28][S:29](=[O:30])(=[O:31])[CH3:32])[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]3[n:12]([n:13]2)[c:14](-[c:21]2[cH:22][c:23]([F:27])[cH:24][cH:25][cH:26]2)[c:15]([NH:17][C:18](=[O:19])[CH3:20])[n:16]3)[cH:6][n:7]1.[Na+:34].[Na+:35].[OH-:33]>>[Cl:1][c:2]1[c:3]([NH:28][S:29](=[O:30])(=[O:31])[CH3:32])[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]3[n:12]([n:13]2)[c:14](-[c:21]2[cH:22][c:23]([F:27])[cH:24][cH:25][cH:26]2)[c:15]([NH2:17])[n:16]3)[cH:6][n:7]1

Participants

6

Reactant 5

HCID 175AcetateHCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 44125499N-(6-(6-Chloro-5-(methylsulfonamido)pyridin-3-yl)-3-(3-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl)acetamide

Product 1

HCID 44125498N-(5-(2-Amino-3-(3-fluorophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-chloropyridin-3-yl)methanesulfonamide

Sources & evidence

ORD record
ord-cb2e737c50094cefa48ade24393c02bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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