Acetone → (RS)-N-(2,3-Dihydro-1-(2-hydroxyethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-1H-indole-2-carboxamide

HRID 1538593Notes

Reaction equation

HRID 1538593 reaction equation
[CH3:41][C:42](=[O:43])[CH3:44].[OH2:40].[nH:1]1[c:2]([C:10](=[O:11])[NH:12][CH:13]2[C:14](=[O:39])[N:15]([CH2:30][CH2:31][O:32][CH:33]3[CH2:34][CH2:35][CH2:36][CH2:37][O:38]3)[c:16]3[c:17]([cH:26][cH:27][cH:28][cH:29]3)[C:18]([c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)=[N:19]2)[cH:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]12>>[nH:1]1[c:2]([C:10](=[O:11])[NH:12][CH:13]2[C:14](=[O:39])[N:15]([CH2:30][CH2:31][OH:32])[c:16]3[c:17]([cH:26][cH:27][cH:28][cH:29]3)[C:18]([c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)=[N:19]2)[cH:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]12

Participants

4

Reactant 3

HCID 180AcetoneHCID 962WaterHCID 14800305(3RS)-1,3-dihydro-3-(2-indolylcarbonylamino)-5-phenyl-1-{2-((RS)-2-tetrahydropyranyloxy)ethyl}-2H-1,4-benzodiazepine-2-one

Product 1

HCID 14800306(RS)-N-(2,3-Dihydro-1-(2-hydroxyethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-1H-indole-2-carboxamide

Sources & evidence

ORD record
ord-0cfd4495b89e4c499337fe81060bd98a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…