3-Chlorobenzoic Acid → Loratadine N-oxide

HRID 1538722Notes

Reaction equation

HRID 1538722 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:27]1)[CH2:7][CH2:8][c:9]1[c:10]([n:11][cH:12][cH:13][cH:14]1)[C:15]2=[C:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:20][CH2:21]1.[Cl:38][CH2:39][Cl:40].[OH:28][C:29]([c:30]1[cH:31][c:32]([Cl:33])[cH:34][cH:35][cH:36]1)=[O:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:27]1)[CH2:7][CH2:8][c:9]1[c:10]([n+:11]([O-:28])[cH:12][cH:13][cH:14]1)[C:15]2=[C:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:20][CH2:21]1

Participants

4

Reactant 3

HCID 4473-Chlorobenzoic AcidHCID 3957LoratadineHCID 6344Dichloromethane

Product 1

HCID 29982763Loratadine N-oxide

Sources & evidence

ORD record
ord-3e6552a0bf87444c9f1c09073fee1b95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…