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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1538754Generated: October 26, 2026

Hydrochloric Acid → N-[(1RS,2SR)-1-(4-tert-butylbenzyl)-2-(3-chlorophenyl)-2-hydroxyethyl]-4-fluoro-1-naphthamide

https://huagongshe.com/reaction/1538754

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant4-Fluoro-1-naphthoic acidHCID 68448—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant(1RS,2SR)-2-amino-3-(4-tert-butylphenyl)-1-(3-chlorophenyl)propan-1-olHCID 22261970—
ProductN-[(1RS,2SR)-1-(4-tert-butylbenzyl)-2-(3-chlorophenyl)-2-hydroxyethyl]-4-fluoro-1-naphthamideHCID 22262222—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-ce5944380c504e87869582b817d7acad
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)