Potassium Cation → N-(2-chloro-4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-6-(trifluoromethyl)phenyl)-3,3-dimethylbutanamide
Reaction equation
[Br:46][c:47]1[cH:48][c:49]([Cl:65])[c:50]([NH:57][C:58]([CH2:59][C:60]([CH3:61])([CH3:62])[CH3:63])=[O:64])[c:51]([C:53]([F:54])([F:55])[F:56])[cH:52]1.[CH3:29][C:30]([CH3:31])([O-:32])[CH3:33].[CH3:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1.[CH:1]1([P:2]([CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2-[c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]2[N:21]([CH3:22])[CH3:23])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1.[F:35][c:36]1[cH:37][c:38]2[c:43]([cH:44][cH:45]1)[CH2:42][NH:41][CH2:40][CH2:39]2.[K+:34]>>[F:35][c:36]1[cH:37][c:38]2[c:43]([cH:44][cH:45]1)[CH2:42][N:41]([c:47]1[cH:48][c:49]([Cl:65])[c:50]([NH:57][C:58]([CH2:59][C:60]([CH3:61])([CH3:62])[CH3:63])=[O:64])[c:51]([C:53]([F:54])([F:55])[F:56])[cH:52]1)[CH2:40][CH2:39]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0192ebd12f434c59b65595c1d4907409
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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