4-(Bromomethyl)-3-fluorobenzonitrile → 4-chloro-N-[(4-cyano-2-fluorophenyl)methyl]-N-(5,5-difluoro-2-oxoazepan-3-yl)benzenesulfonamide
Reaction equation
[Br:22][CH2:23][c:24]1[c:25]([F:32])[cH:26][c:27]([C:28]#[N:29])[cH:30][cH:31]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[CH2:23][c:24]2[c:25]([F:32])[cH:26][c:27]([C:28]#[N:29])[cH:30][cH:31]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-8802928d92784159abd929e1a9d88d5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…