Methanol → 7-methoxy-3-(piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one

HRID 1538917Notes

Reaction equation

HRID 1538917 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:15](=[O:27])[NH:16][c:17]3[c:18]([cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]3)[CH2:19][CH2:20]2)[CH2:12][CH2:13]1.[CH3:30][OH:31].[H:28][H:29]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:15](=[O:27])[NH:16][c:17]3[c:18]([cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]3)[CH2:19][CH2:20]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 887MethanolHCID 596268033-(1-Benzylpiperidin-4-yl)-7-methoxy-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 183568527-methoxy-3-(piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one

Sources & evidence

ORD record
ord-3ed39837715045bd858262e335c2ebda
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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