2,4-Dichloro-5-fluoropyrimidine → 2-chloro-N4-(3,4-difluoromethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine

HRID 1539004Notes

Reaction equation

HRID 1539004 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[F:10][c:11]1[c:12]2[c:13]([cH:18][cH:19][c:20]1[F:21])[NH:14][O:15][CH2:16][O:17]2>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:14][c:13]2[c:12]3[c:11]([F:10])[c:20]([F:21])[c:19]([cH:18]2)[O:15][CH2:16][O:17]3)[n:7]1

Participants

3

Reactant 2

HCID 2507052,4-Dichloro-5-fluoropyrimidineHCID 66759615HCID 66759615, compound

Product 1

HCID 220602142-chloro-N4-(3,4-difluoromethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine

Sources & evidence

ORD record
ord-fb64ce17d2a64fcc917c42cfac836dc8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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