2-Chloromethyl-4-(beta-trimethylsilylethoxymethoxy)-naphthalene → tert-butyl (3RS,4RS)-3-[4-(2-trimethylsilanyl-ethoxymethoxy)-naphthalen-2-ylmethoxy]-4-[4-(2-trityloxy-ethyl)-phenyl]-piperidine-1-carboxylate
Reaction equation
[Cl:43][CH2:44][c:45]1[cH:46][c:47]([O:55][CH2:56][O:57][CH2:58][CH2:59][Si:60]([CH3:61])([CH3:62])[CH3:63])[c:48]2[cH:49][cH:50][cH:51][cH:52][c:53]2[cH:54]1.[OH:1][CH:2]1[CH2:3][N:4]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([CH2:14][CH2:15][O:16][C:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([CH2:14][CH2:15][O:16][C:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:12][cH:13]1)[CH2:44][c:45]1[cH:46][c:47]([O:55][CH2:56][O:57][CH2:58][CH2:59][Si:60]([CH3:61])([CH3:62])[CH3:63])[c:48]2[cH:49][cH:50][cH:51][cH:52][c:53]2[cH:54]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ca488e49966d4b478863072c340bbce9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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