Dichloromethane → 3-(1-{[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]sulfonyl}-4-piperidinyl)-5-phenyl-1H-indole-7-carboxamide

HRID 1539383Notes

Reaction equation

HRID 1539383 reaction equation
[Cl:42][CH2:43][Cl:44].[O:25]=[C:26]1[N:27]([CH2:36][CH2:37][S:38](=[O:39])(=[O:40])[Cl:41])[C:28](=[O:35])[c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]21.[c:1]1(-[c:7]2[cH:8][c:9]3[c:10]([CH:19]4[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]4)[cH:11][nH:12][c:13]3[c:14]([C:16](=[O:17])[NH2:18])[cH:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][c:9]3[c:10]([CH:19]4[CH2:20][CH2:21][N:22]([S:38]([CH2:37][CH2:36][N:27]5[C:26](=[O:25])[c:34]6[c:29]([cH:30][cH:31][cH:32][cH:33]6)[C:28]5=[O:35])(=[O:39])=[O:40])[CH2:23][CH2:24]4)[cH:11][nH:12][c:13]3[c:14]([C:16](=[O:17])[NH2:18])[cH:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 3087392-Phthalimidoethanesulfonyl chlorideHCID 114271625-Phenyl-3-(4-piperidinyl)-1H-indole-7-carboxamide

Product 1

HCID 590033673-(1-{[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]sulfonyl}-4-piperidinyl)-5-phenyl-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-9c82398fe8394b4f859658a38e6d183e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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